Case Scenario 

Melissa, 38, recently had some progesterone pessaries dispensed at your pharmacy. She tells you she won’t need a repeat as her in-vitro fertilisation (IVF) cycle was unsuccessful. Melissa becomes teary as she explains that she will need to start a frozen egg (oocyte) cycle, as the first fresh transfer did not result in a pregnancy. She says she wasn’t really listening when they informed her about what would happen if the first transfer wasn’t successful, as she was so hopeful it would work the first time. She asks what medicines she can expect this time.

Learning Objectives

After reading this article, pharmacists should be able to: 

  • Discuss the medicines used for in-vitro fertilisation 
  • Describe the adverse effects of the medicines used for in-vitro fertilisation 
  • Describe the role of pharmacists in assisting patients undergoing in-vitro fertilisation. 

Competency (2016) standards addressed: 1.1, 1.4, 1.5, 2.2, 3.1, 3.5 

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Introduction 

Infertility is defined by the World Health Organization as ‘a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse’.1 An alt

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